high resolution ultrasonic spectroscopy for analysis in biocolloids

Vitaly Buckin, Evgeny Kudryashov, Siobhan Morrissey

International Labmate, Vol 27 Issue 2, pp. 23-24 (2002)

Ultrasonic spectroscopy is a non-destructive analytical technique based on the measurements of parameters of low energy ultrasonic waves propagating through analysed samples. The analytical power of ultrasound is well known through its application in medicine, where the ability of ultrasonic waves to propagate through opaque biological tissues is used for visualisation of internal parts of a patientís body, analysis of blood stream and others. In spite of this and other successful application of ultrasound in certain fields of material analysis limited resolution of the measurements and complicated cleaning and sample handling procedures prevented a wide spread of this technique in research and analytical laboratories. Resent progress in modern technologies lead to high-resolution spectrometers, which overcome these limitations, thus making commercial ultrasonic instruments available for a wide spectrum of analytical tasks. These instruments can perform analysis in a broad range of sample volume (0.03 ml to 20ml) and in various regimes with a record. In the present paper we describe the application of high-resolution ultrasonic spectroscopy for analysis of gelation processes and coagulation in milks, formation of micelles and ligand-protein binding.

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